Some situations require multiple private endpoints (using the Private Link service) to be created per region. This is not currently supported for multi-region replica sets.

One scenario is especially for when there is a shared VPC/VNet for initial transit from on-prem to cloud plus another VPC/VNet for an application. Both of those VPC/VNets would want a Private Endpoint to connect directly to the Atlas cluster. Even if it is possible (sometimes is not), routing traffic via multiple VPC/VNets would mean 3 hops to Atlas from on-prem